Archive February 16, 2023

Can Medical Cannabis impair Our Defence Mechanisms?

Medical Cannabis

Preliminary studies suggest that cannabis may have an immunosuppressive effect. Though this holds promise for treating disorders brought on by an overactive immune system, it may put otherwise healthy people at greater risk of infection. However, how cannabis affects immunological function is still poorly understood. Here, you may read what the research has to say.

The Functioning of the Immune System

Let’s quickly review how the immune system functions before we go into how medical cannabis could affect immunity. Two main types of physiological defence exist: innate immunity and adaptive immunity.

Every living thing has an initial line of defence against outside invaders called the innate (or universal) immune system. The skin and the mucous membranes (the lining of the nose, mouth, lungs, and other organs and cavities) are all part of this system, which works together to keep harmful bacteria at bay.

Enzymes, acids, and mucus are all used by these biological barriers to prevent the spread of bacteria and viruses. A subset of the cells that make up the innate immune system are phagocytes, which are specialised to digest dead or dying organisms. The word “phago” comes from the Greek word “phagein,” which meaning “to eat.” Indeed, phagocytes live true to their moniker by enclosing and “eating” invading microbes.

Our adaptive (or acquired) immunity is considerably more targeted and effective than our innate immunity, which relies on a more brute-force approach to eliminating invaders. The adaptive immune system kicks in as backup if our innate defences fail, and it begins to recognise the invader and produce antibodies tailored to destroy it.

Does marijuana help or hurt the immune system?

Without a functional immune system, human beings would not survive for long. Bacteria, fungi, and viruses are everywhere around us, waiting for the chance to invade our bodies and feast on our cells.

Our immune system is a multi-layered defence system consisting of a wide variety of organs, cell types, and proteins that work together to combat harmful environmental factors. They aren’t always effective enough, though, to stop an illness in its tracks.

We all become sick from time to time, but because to our immune systems’ ingenuity, we always recover better and are better prepared to fight off future bouts of the common cold, influenza, and other contagious illnesses.

Many people try to improve their immune systems through diet, exercise, behavioural modifications, and dietary supplements in order to lessen their susceptibility to illness.

Connecting the Dots: Cannabis, the Immune System, and the Endocannabinoid System

The immune system, like every other part of the body, cannot function alone. The endocannabinoid system is a term familiar to cannabis experts (ECS).

While researching the physiological effects of cannabis, scientists stumbled onto the components of this system. They eventually learned that it has a presence in every organ and system, from the central nervous system and skeleton to the skin, gastrointestinal tract, and immune system.

The ECS was named the “universal regulator” of the human body because of its role in maintaining homoeostasis, or internal stability.

Both CB1 and CB2 receptors, signalling chemicals anandamide and 2-AG, and enzymes involved in endocannabinoid biosynthesis and catabolism make up the classical ECS.

These components are widespread in the immune system and play important roles in immunological regulation, homoeostasis maintenance, and modulation.

CB1 and CB2 receptors are found on many different kinds of immune cells, such as B cells, natural killer cells, monocytes, CD8 and CD4 lymphocytes, and many more. This is where endocannabinoids come in, since their binding to these receptors helps to control processes like the body’s inflammatory response.

The Influence of Marijuana on the Body’s Defense Mechanisms

Due to its close relationship with the ECS, cannabis may serve as a physiological defence mechanism modifying agent. You see, the structure of endocannabinoids (which occur naturally in the body) and phyto-cannabinoids (which occur naturally in plants) is quite similar.

This suggests that cannabinoids from the outside, such as THC and CBD, may be able to attach to ECS receptors, modulate enzyme activity, and behave in a manner similar to that of endocannabinoids. Plant cannabinoids may provide a means of “hacking” the ECS in regards to immunity, as our endocannabinoids exert considerable control over our immune system.

Illnesses Caused by the Immune System

The immune system may sometimes go awry. Autoimmune illnesses occur when the body’s immune cells mistake healthy tissues like skin, joints, and nerves for harmful pathogens like bacteria and viruses.

Inflammatory cascades triggered by this self-inflicted harm manifest as symptoms including lethargy, muscular pain, fever, hair loss, and rashes. Rheumatoid arthritis, psoriatic skin disease, and multiple sclerosis are all examples of auto-immune disorders.

Some of the earliest studies to focus on the anti-inflammatory effects of cannabis focused on their ability to halt the development of autoimmune diseases. Evidence from animal and cell research also points to a possible immunosuppressive impact of cannabis.

Virus Infection and Immune System Dysfunction

Is it possible that cannabis might help viruses and other infectious infections by suppressing the immune system? Certainly, that’s not out of the question. This may explain why chronic and heavy cannabis users have lower immune systems and a greater propensity to contract and spread diseases.

Even more concerning, the few available evidence shows that chronic cannabidiol (CBD) usage may activate myeloid-derived suppressor cells (MDSCs), which dampen the immune system and may raise the risk of cancer. There is continuing research looking into the effects of some cannabis compounds on pathogenic viruses and bacteria, despite the chemicals’ effects on the immune system.

Smoking marijuana and getting HIV

Spread of the human immunodeficiency virus (HIV) occurs predominantly through unprotected sexual activity. Once inside, the infection operates like a parasite, destroying the body’s defences.

HIV induces flu-like symptoms and a large decrease in CD4+ T cells, which aid in recruiting additional immune cells in the face of infection, in the early stages of infection. The virus will continue to multiply even after the first symptoms have subsided, but it may take years before it manifests itself again.

Subtly but persistently, it weakens and compromises the immune system, leading to immunocompromised status.

See Also: Can CBD Oil Help for Tinnitus?

It seems to reason that those living with HIV should steer clear of cannabis as scientists investigate the plant’s immunosuppressive effects. Many of them, however, utilise the plant, according to polls.

The potential benefits of cannabinoids for lowering viral replication and increasing T cell numbers are being studied alongside the potential risks of cannabis use in HIV patients.

Degenerative Neurological Diseases

Neurodegeneration is a hallmark of multiple sclerosis, an autoimmune illness. Inflammation of the central nervous system is initiated by immune cells. Myelin is a fatty encasing that surrounds and insulates nerve cells, and the cells acquire a taste for it throughout this process.

This attack, when sustained, can destroy the protective covering of the nerves, known as myelin, and eventually disrupt the normal firing patterns of the nervous system. Ongoing research is examining the CB1 receptor and drugs that bind to this location for their possible neuroprotective effect.

Does Cannabis Help or Hurt the Immune System?

There is not enough information for us to answer your question with certainty at this time. There is some indication that the herb possesses immunosuppressive qualities that may have some therapeutic use; however, if this is the case, it may also pose some risks for people with impaired immune systems and heavy herb users.

As a result, further studies involving actual people are required before we can reach a definitive conclusion.


We know you might be curios to find out more information and discuss medical cannabis treatment, or where to get legal medicinal cannabis products in Australia, who is authorised to prescribe medicinal cannabis products to you, and we know lots of people are also worried about the use of medicinal cannabis.

For all these inquiries; including most medicinal cannabis products available on the market, prescribing medicinal cannabis, information about smoked cannabis, how to bring medicinal cannabis product on a travel, medical conditions that can be cured by medical cannabis products, recreational cannabis, other general use of cannabis, you should schedule a consultation session today with our experts at Chronic Therapy to get medical professionals advice about any of the above mentions.

Can CBD Oil Help for Tinnitus?


Tinnitus is an audiological and neurological ailment that affects millions of people around the world. However, medical science has not yet discovered a solution for the condition. As a consequence of this, those who experience tinnitus are forced to look for any kind of relief they may get. Cannabidiol, often known as CBD, may be an option for some people as a result of this.

CBD oil from cannabis plant has gained popularity due to claims that it can alleviate a wide range of symptoms, including those of insomnia, chronic pain, and anxiety. The ringing in the ears may even be reduced, according to some users.

Is there evidence to support this, though? Here, you’ll find out.

What is Tinnitus?

Hearing sounds or ringing in the ears that have no external cause is known as tinnitus. The elderly is disproportionately affected, yet anyone can get the condition.

The level of distress caused by tinnitus varies from person to person, but for some, the persistent buzzing, roaring, or ringing can be intolerable.

Tinnitus is not a disease but rather a symptom of an underlying problem. The following are some possible explanations:

  • degeneration of the auditory system with aging
  • high cholesterol with blood pressure
  • constant exposure to noisy environments
  • Muscle spasms in the middle ear
  • injures to the head or neck
  • Ear or auditory nerve tumors in patients with Meniere’s disease
  • excessive ear wax buildup
  • problem with the jaw’s temporomandibular joint

Can CBD Oil Help for Tinnitus?

CBD CBD from cannabis sativa plant for tinnitus has had conflicting results in the scientific literature. A 2015 study in animals found that combining CBD and THC worsened tinnitus.

There is not enough evidence from animal or human trials to confirm that medical cannabis can help relieve tinnitus, according to a more recent evaluation of studies from 2020.

However, a 2020 study revealed that CBD might aid with hearing loss and tinnitus due to its anti-inflammatory and neuroprotective effects. However, additional study is required, especially in human subjects.

CBD may help with tinnitus-related symptoms like stress and sleeplessness, but it may not be a solution.

Further Research on CBD And Tinnitus

It is essential to know that the quality of products sold on the commercial market is not governed by any standards and might vary greatly. Products that include hemp seed oil, for instance, but do not really contain any CBD in their formulations. 

There is still a significant lack of accessibility to medical cannabis from CBD, as it is almost exclusively sold in dispensaries located in places where marijuana has been legalized, either for THC or CBD, or both. 

Both cannabinoid receptors CB1 and CB2 have been identified in the brain, and both respond favorably to the presence of cannabis and CBD. New evidence suggests these receptors contribute to both balance and hearing. This has prompted some to speculate that CBD supplementation could alleviate the symptoms of hearing problems like tinnitus. However, there is not a great deal of data available.

CBD oil was used to treat lab rats with tinnitus in 2015, but the results showed that it had no beneficial effects and, in some cases, actually made the condition worse (in rats, at least). In order to make any firm results, human research is required, as indicated in a 2020 literature analysis.

Tinnitus sufferers often struggle with stress, but there’s some hope that cannabidiol (CBD) could assist. A study published in Neurotherapeutics in 2015 found that CBD was helpful in lowering anxiety behaviors associated with post-traumatic stress disorder (PTSD), seasonal affective disorder (SAD), and obsessive-compulsive disorder (OCD). 

Similarly, information about potential adverse effects is scarce. When used with other drugs, such as blood thinners, CBD can have negative side effects.

Is it Safe to Use CBD Oil for Tinnitus?

According to the World Health Organization, CBD is usually safe for most people and is unlikely to cause negative effects.Some of the possible adverse effects are lack of or increase in weight, exhaustion, and nausea.

Consult your doctor before trying CBD, especially if you are already on any drugs, even if any potential adverse effects are likely to be minor. There is a possibility that CBD could interact with a number of common pharmaceuticals.

It’s also worth noting that CBD products are not governed by the FDA. The Food and Drug Administration has strict regulations in place for companies that make fraudulent claims, but this does not mean that all CBD products available without a prescription are risk-free and beneficial.

If you want to make sure you’re getting a good product, you’ll have to look into it on your own.

What CBD Product is Best for Tinnitus?

CBD oil is preferable to other forms of CBD because of its greater absorption and capacity to induce whole-body effects; nonetheless, there is no evidence that CBD can aid with tinnitus. However, ensure to choose a product that addresses a wide range of symptoms to maximize the entourage effect.

Should You Try CBD for Tinnitus?

Experts explain that tinnitus patients often have high levels of mental distress from the constant ringing in their ears, so anything that helps with stress relief is appealing. However, it’s only been recent that they’ve taken to utilizing CBD.

Notwithstanding, they acknowledge that a major difficulty with CBD is that everyone reacts differently. What’s the right dose for me can be too high or low for you. In addition, not everyone has the same reaction. Some individuals feel it right away. Some people need to take it consistently for a couple of weeks before they see any results. 

In addition, there are those who feel absolutely nothing. Unfortunately, finding what works best for you requires a degree of experimentation. The work was certainly worth it to me.


CBD oil, cannabis oil and cannabidiol CBD has been used consistently in the treatment of conditions such as chronic pain, anxiety disorders, cancer treatment, multiple sclerosis, post traumatic stress disorder, and for other health benefits. To know more about buy CBD oil Australia and other hemp seed oil benefits, you should book a consultation session with a professional from Chronic Therapy today.

If you are also looking for information about scientific evidence that support both CBD oil and other medicinal cannabis products usage, you are in the right place. You will also be informed about every adverse effects, preclinical evidence, and symptoms related to CBD and hemp seeds, including their potential health benefits, hemp derived CBD products and dietary supplements, how cannabidiol reduces cigarette consumption and as a potential anticancer drug; where to buy CBD oil legally and state medical marijuana laws.

More to read: Can Medical Cannabis impair Our Defence Mechanisms?